If you have done a partial gene sequence for a service like ancestry or 23andme you can just look at the raw data and search for the known polymorphisms.

Methylated B vitamins and vitamin D were life changing discoveries. I have some polymorphisms (VDR and MTHFR) that mean I am less efficient at absorbing them from food. 2000 IU a day and a B-complex ended chronic depression/anxiety and insomnia for me. Those mutations are pretty common so I highly recommend trying them for anyone with similar issues.

Aside from that I think a whole foods plant based diet with some eggs and fish and no refined sugars is probably the way to go. Some micronutrients like vitamin A and K2 are more easily absorbed from animal sources, so eating a small amount of meat and/or eggs is probably a bit healthier than pure plant based IMO.

I quite like Fastmail. It’s a bit expensive but the service is very reliable and they have a well established reputation. You can create masked emails using their domain or your own from the web interface.

Framework. I’ve run Debian, Fedora and for a while now NixOS, all of which have worked flawlessly.

I did have to replace the heatsink/fan part on mine because the fan bearing started clicking, but I’m sure that was just a first generation product issue (I was one of the first batches). I was glad to be able to do the replacement myself at relatively low cost and the process couldn’t have been easier (took about 30 minutes).

My previous machine was a 2013-ish ThinkPad X series and the Framework absolutely blows it out of the water. I’m looking forward to upgrading mine to a Ryzen motherboard sometime in the not so distant future.