For me it’s driving while under the influence. If you couldn’t tell, I like me some ganja. However I have long since held the belief that it is utterly insane to drive while under the influence of most substances, with maybe nicotine and caffeine being the exception. All too often I see other stoners smoking and driving, which I simply can’t fathom. I’ve only operated a vehicle once under the influence and it was just to move a U-Haul around the block to a different parking spot, which was such a scary experience while high that I refuse to even consider getting behind the wheel again while high.
Some substances help with tasks such as operating machinery for extended periods e.g. stimulants in the amphetamine class of drugs, methamphetamine, dexamphetamine, etc. Cocaine is probably also helpful.
https://en.m.wikipedia.org/wiki/Dextroamphetamine
It doesnt help with operating machinery, it helps with not falling asleep while doing it. Sleep deprived/exhausted people shouldnt be operating heavy machinery and definitely, shouldnt be taking highly addictive drugs to enable them to do it either. Its sad that their work conditions sometimes forces them to do so.